Northeastern University Professional Programs · Courses
BIOT
54 courses with the subject BIOT, each shown exactly as we captured it from the college's catalog, with every element we hold. Where the wording looks broken, that is our reading of the catalog, not the college's text.
BIOT 5120Foundations in Biotechnology3
Provides an interdisciplinary, state-of-the-art introduction to biotechnology. Covers the molecular foundations of biotechnology, molecular microbiology, receptor pharmacology, drug development processes, biotech process development and scale-up, drug approval and regulatory affairs, genomics, microarray analysis, proteomics, computational biology, molecular modeling, analytical biotechnology, and bioterrorism and biotechnology.
Introduces selected key skills and techniques central to life sciences research. Combines hands-on training in basic laboratory skills with lecture and live demonstration. Laboratory exercises highlight the importance of precision/accuracy in dispensation of liquids and in the preparation of solutions and standards, documentation and record keeping, and maintaining a safe and sterile work environment while performing scientific research.
Introduces essential laboratory skills and techniques fundamental to life sciences research through hands-on training, demonstrations, and data analysis. Covers precision and accuracy in liquid dispensation, preparation of solutions, and standards; proper documentation and recordkeeping; and maintenance of safe, sterile work environments. Combines practical laboratory exercises with instructional content across four modules to build foundational competencies in scientific research practices.
Exposes students to the business of biotech from scientific discovery startup through its product launch and subsequent organizational and scientific pipeline growth. Topics include scientific discovery, biotech-related funding and organizational structures, regulatory and clinical trial considerations, biotech alliances, patient access, ethics and compliance, and commercialization and growth while meeting unmet patient or consumer needs in this highly regulated industry. Although the focus is on the highest regulated standards in biopharma, the course also touches upon various aspects of other biotechnology domains.
Introduces the fundamental molecular interactions involved in immunological responses as well as in measuring and testing in a research and regulated environment. Other drug-safety-related topics include adventitious agents (viruses, microorganisms, mycoplasma) and risk factors such as product-related substances (aggregates and post-translationally modified variants), endotoxins, DNA, host-cell proteins, process contaminants such as antibiotics, and the means of testing and removing these through validated processes.
BIOT 5340Introduction to Biotherapeutic Approvals3
Introduces students to biologics. The class of drugs referred to as biologics or biotherapeutics, proteins drugs, makes up a large portion of the drugs in development and on the market today. Focuses on considerations for approval for such drugs. Offers students an opportunity to learn how to be able to describe and explain both biologics and biosimilars.
BIOT 5401Scientific Communication and Problem Solving in Biotechnology3
Provides an in-depth examination of the principles and practices of scientific writing, academic integrity, literature analysis, and scientific problem solving. Focuses on effective communication of scientific ideas through various writing genres, including research articles, presentations, and proposals. Explores ethical considerations and best practices in scientific research, including issues related to plagiarism, data falsification, Good Documentation Practice (GDP), and authorship. Emphasizes critical skills in literature analysis and data presentation, including the evaluation and presentation of novel data sets and research articles and the effective integration of scientific literature into writing.
Introduces the science that supports regulatory affairs in the biopharmaceutical industry. Focuses on the methods and instruments used to characterize the processes and products of biotechnology including the production, separation, purification, characterization, and formulation of biologics; the pharmacokinetics of proteins; chemical and biological equivalencies of biogenerics; stability testing; high throughput assays; cell system expression; variants; method validation; and quality control.
Focuses on the fundamental principles and elements in the process of manufacturing biopharmaceuticals. Covers kinetics of enzymatic reactions; selected microbial and cell metabolism and relevant control mechanisms; kinetics of cell growth, cell death, substrate consumption, and product formation; mathematical modeling and representation of bioprocesses; examples of industrial bioprocesses to illustrate types and operations of upstream and downstream unit operations and mass transfers in fermentation systems—the affecting factors and the impact on process development and scale-up. Also includes an overview of economic considerations. Emphasizes bioprocesses for recombinant protein production.
Discusses the fundamentals in structural biology and biochemistry in drug design and applied biotechnology with special focus on protein chemistry. Explores the nature, structure, and function of proteins in the context of analytical analysis, molecular medicine, and drug discovery. Emphasizes bioinformatics and computational systems biology. Specifically investigates the analysis of ongoing research projects, case studies, and practical concepts of biotechnology.
BIOT 5630Cell Culture Applications for Biopharmaceuticals2
Covers principles and concepts in mammalian and other cell culture processes for biopharmaceutical manufacturing with the goal of providing a solid foundation in biopharmaceutical production. Topics include cell line development for protein expression; batch, fed-batch, and perfusion processes; media development; bioreactor operations; impeller designs; bioprocessing, including scale up and scale down; and advancements in cell culture techniques. Emphasizes quality assurance within a current good manufacturing practices environment and examines the entire bioprocessing workflow.
BIOT 5635Downstream Processes for Biopharmaceutical Production3
Addresses the development of recombinant protein purification processes in biotechnology. Provides an overview of the scientific principles, engineering strategies, and unit operations facilities involved in scalable protein purification processes. Also discusses viral clearance and inactivation strategies; cGMP considerations; and technological advances to improve effectiveness and efficiency, such as membrane-based disposable systems.
BIOT 5640Drug Product Processes for Biopharmaceuticals3
Prerequisite(s): BIOT 5621 with a minimum grade of C- or BIOT 5621 with a minimum grade of C- or CHEM 5620 with a minimum grade of C- or CHEM 5620 with a minimum grade of C-
BIOT 5700Molecular Interactions of Proteins in Biopharmaceutical Formulations3
Prerequisite(s): (BIOT 5621 with a minimum grade of C- or BIOT 5621 with a minimum grade of C- ) or (CHEM 5620 with a minimum grade of C- or CHEM 5620 with a minimum grade of C- )
Discusses applications of concepts in molecular biology and biochemistry. Focuses on understanding the theory behind common techniques used in biotechnology. Topics include principles and methods for genetic manipulation, gene expression, nucleic acid sequencing, microarrays, and epigenomics. Emphasizes molecular signaling pathways, as well as primer and guide RNA design. Offers students an opportunity to practice proposal writing and other professional skills.
Provides an overview of specific gene therapy applications and diseases that are, or may be, a target of gene therapies. Includes case study analysis of gene therapies with publicly available information, as well as tools for proper identification of gene targets in disease states.
BIOT 5810Cutting-Edge Applications in Molecular Biotechnology3
Introduces the uses of molecular biology in a biotechnology setting. Includes a brief review of the basics and then dives into state-of-the-art molecular biology applications used in biotechnology today. These applications include stability and expression of cloned gene products, gene cloning strategies, transgenic species, mutation creation and analysis, DNA fingerprinting, PCR technology, microarray technology, gene probes, gene targeting, gene therapy, stem cell technology, antisense RNA, CAR T-cell therapy, RNA interference, and CRISPR/Cas9.
BIOT 5830Regulatory Landscape of Cell and Gene Therapies2
Introduces the current state of regulatory approvals for cell and gene therapies. Focuses on the scientific and technical considerations for approval for such drugs in the United States, in Europe, and in other key global markets. Explores the scientific challenges in the context of regulatory approval of these products, as well as how the process differs from traditional biotherapeutic product approvals. Examines how these regulatory pathways are evolving with a specific emphasis on quality, efficacy, and safety throughout the product life cycle (manufacturing through commercialization).
Prerequisite(s): BIOL 5821 (may be taken concurrently) with a minimum grade of C- or BIOL 5821 (may be taken concurrently) with a minimum grade of C- or BIOL 5821 (may be taken concurrently) with a minimum grade of C-
Offers a comprehensive look at various aspects of higher- order protein structures in biotherapeutics and their implications on biological drug design. Focuses heavily on protein aggregation, a type of HOS, and analysis of those aggregates including functional implications. Topics include a review of protein structure, protein aggregation, functional aspects, and techniques to reduce HOS using protein expression and purification strategies, protein folding in disease, macromolecular crystallography, nuclear magnetic resonance, analytical ultracentrifugation, circular dichroism, light scattering, electron spin labelling, cryo-EM, WAXS, and HDX-MS. Highlights experimental design and application to the biotechnology industry in identifying and reducing HOS.
BIOT 5900Emerging Innovations in Biotechnology and Pharma3
Explores emerging scientific and technological innovations in biotechnology and pharmaceutical development. Introduces data-driven approaches, machine learning concepts, and analytical methods used across discovery and manufacturing. Examines how these tools shape target identification, molecular design, diagnostics, and bioprocess optimization. Reviews ethical and societal considerations related to digital technologies in the life sciences. Surveys national and international regulatory frameworks, including guidance for AI/ML applications. Students analyze datasets, interpret computational results, and evaluate regulatory documents. Emphasizes clear, professional communication of scientific and policy insights while highlighting how technological and regulatory advances influence decisions across the biopharmaceutical landscape.
Emphasizes the importance of using vaccines in order to prevent the spread of infectious diseases and viruses. Discusses the evolution of vaccines throughout medical history (e.g., smallpox, polio), emphasizing lessons learned so they can be adapted to development of new and novel vaccines. Explains the molecular mechanism of how vaccines, such as vaccines that use attenuated virus to more novel vaccines that use mRNA, elicit an immune response. Examines the importance of immunization in the context of the immune system.
BIOT 5920Foundations in Vaccine Regulatory Science3
Explores the science behind how regulatory pathways were developed and how vaccines were approved for human use. The pathway for vaccine approvals by national regulatory authorities has been well established for decades. The SARS-CoV-2 pandemic created an immediate need to create new vaccines, which also created a new need for the regulatory approval of these vaccines. Examines how SARS-CoV-2 vaccines caused an increased interest in the regulatory science behind vaccine regulatory approval, specifically exploring the use of emergency use authorization (EUA) in getting SARS-CoV-2 vaccines to market. Discusses how the use of EUAs changed the regulatory science landscape of vaccines.
Discusses the molecular tools used for vaccine design and development, including the experimental tools used for attenuated whole-organism vaccines, purified macromolecule vaccines, and DNA or mRNA vaccines. Emphasizes vector design and development and specifically the challenges associated with vaccine design and development. Also studies computational tools that aid vaccine development.
Offers students an applied project setting in which to apply their curricular learning. Working with a sponsor, students refine an applied research topic, perform research, develop recommendations that are shared with a partner sponsor, and create a plan for implementing their recommendations. Seeks to benefit students with a curriculum that supports the development of key business communication skills, project and client management skills, and frameworks for business analysis. Offers students an opportunity to learn from sponsor feedback, review 'lessons learned,' and incorporate suggestions from this review to improve and further develop their career development and professional plan. May be repeated twice.
Explores the key agricultural biotechnology (agritech) principles and methods that are used in industry today; serves as a foundational course exposing students, briefly, to all aspects of agritech. Topics covered include gene transfer and genetic modification; cloning; plant biotechnology, animal science, food and ecological biotechnology; consumer concerns; safety testing; and other issues related to agritech.
Explores the principles of experimental design and statistical analysis. Emphasizes research in the molecular and biological sciences and biotechnology. Topics include probability theory, sampling hypothesis formulation and testing, and parametric and nonparametric statistical methods.
Presents concepts, tools, and techniques for real-world, on-the-job application of quality that is practical for a wide range of organizations. Offers an insight into the mindset of quality, along with an overview of the concepts, principles, processes, and activities involved in quality assurance, quality control, and regulatory compliance within the life sciences Industry. Emphasizes understanding the business of biotech; the remit of global regulatory agencies; principles and processes for establishing and enforcing regulation and guidance; quality management systems, operations, and compliance; quality leadership; quality planning; and careers in the quality profession. Includes presentations from a variety of industry experts.
Studies those microorganisms associated with the manufacture of pharmaceuticals, including biopharmaceuticals. Focuses on how to exclude microorganisms, such as exotoxins and endotoxins, from pharmaceutical processes to produce a sterile product. Considers how products react to microorganism contamination and methods of disinfection. Discusses pharmaceutical microbiology as related to clean rooms and controlled environments and methods and specifications related to microorganisms based on the United States Pharmacopeia guidelines. Lastly, discusses facility monitoring, specifically EM/critical utility testing, process monitoring, and maintenance throughout with an emphasis on what regulators expect to see in terms of data.
Focuses on the laws and regulations related to pharmaceuticals manufacture and administration. Discusses an overview of laws and regulations and provides guidance in the context of why they exist, their evolution, and implementation. Specifically focuses on the laws and regulations around good manufacturing practices (GMP), postapproval safety concerns, regulation of manufacture, violations and enforcement, and what to expect during an inspection from a regulatory body. Surveys the laws and regulations on a global level focusing on specific examples related to the United States, Europe, Asia, and other regulatory agencies.
BIOT 6320Design and Development of Biopharmaceuticals3
Focuses on the production and processes related to the design and development of pharmaceuticals, especially biopharmaceuticals. Discusses the implementation of a quality management system plan including document processes, procedures, metrics, reporting, and responsibilities aligned with pharmaceutical and biotechnology companies’ business objectives. Emphasizes signaling problems (continual improvement plans), transparency, validation, and team cooperation/dynamics. Topics may include data management, product quality, and quality instruments. Specifically discusses the International Council for Harmonisation Q10 guidelines.
Discusses the importance of sterile operations in producing drug products, as part of good manufacturing practice (GMP). Emphasizes sterile manufacturing operations for all drugs.
Introduces the cooperative education program. Offers students an opportunity to develop job-search and career-management skills; to assess their workplace skills, interests, and values and to discuss how they impact personal career choices; to prepare a professional resumé; and to learn proper interviewing techniques. Explores career paths, choices, professional behaviors, work culture, and career decision making.
Examines the probable weapons of biowarfare—including biological, chemical, and nuclear weapons— from several perspectives. Offers fundamental information on the biology and mechanism of action of the most important potential agents of terror and an introduction to the role of government. Topics include biological impact, detection and recognition, epidemiology, and treatment. Evaluates potential dangers and effectiveness and investigates strategies for defense against attacks by such weapons. Discusses the bioethical challenges of anti-bioterror research. Also offers students an opportunity to develop skills in scientific literacy and writing.
Examines the national and international political, legal, and policy dimensions of response to threats of bioterrorism and resurging epidemics. Explores how the interagency community works at local, tribal, state, national, and international levels to meet these growing challenges. Resurging epidemics are now gaining national attention in a way not seen for generations. These threats join the long-standing challenges of potential domestic and foreign state-sponsored biowarfare attacks and the growing awareness of the threat of bioterrorism.
BIOT 6650Polymerase Chain Reaction Techniques and Assay Optimization1
Prerequisite(s): (BIOT 5145 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- ) or Biotechnology Lab Skills with a score of 80
BIOT 6900AI-Powered Biotech Workflows: From Discovery to Clinic3
Explores artificial intelligence applications across the therapeutic development pipeline, from target discovery through clinical implementation. Covers multi-omics data integration, protein structure prediction with AlphaFold, molecular docking and drug design, ADME-Tox prediction, knowledge graphs for drug repurposing, and generative AI for molecule design. Examines clinical data analysis using natural language processing, medical imaging AI, multimodal data integration for precision medicine, and computational approaches to clinical trial design. Emphasizes biological interpretation of AI outputs and integration with experimental workflows. Offers students an opportunity to obtain hands-on experience with industry-standard computational tools using real biological datasets and to build competencies for roles in computational biology, bioinformatics, and AI-enabled drug discovery.
Offers students an opportunity to integrate and apply the skills learned in earlier courses to an independent project supervised by a faculty mentor. The goals of the capstone are to develop skills in communicating the results of independent projects; increase student awareness of research in biotechnology outside of their own work; demonstrate a familiarity with the literature background to their work, including a working knowledge of literature searching; and provide an opportunity to reflect on individual progress toward a career in biotechnology.
Prerequisite(s): (BIOL 4707 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- ) or Biotechnology Lab Skills with a score of 80
Prerequisite(s): (BIOT 5145 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- ) or Biotechnology Lab Skills with a score of 80
Prerequisite(s): BIOT 5145 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- or BIOT 5145 with a minimum grade of C- or Biotechnology Lab Skills with a score of 80
Subject
BIOT
Credits (min)
3
Credits (max)
3
Credit unit
Hours
Type
course
Repeatable
May be repeated once for credit with distinct research focus areas.
Presents selected topics of current importance in biotechnology. May be repeated five times for a maximum of 6 total semester hours. Campus Locations Arlington VAOpens New Window Boston MAOpens New Window Burlington MAOpens New Window Charlotte NCOpens New Window London UKOpens New Window Miami FLOpens New Window Nahant MAOpens New Window New York City NYOpens New Window Oakland CAOpens New Window Portland MEOpens New Window Seattle WAOpens New Window Silicon Valley CAOpens New Window Toronto ONOpens New Window Vancouver BCOpens New Window Quick Links Registrar Opens New Window Directory Opens New Window Libraries Opens New Window Emergency Information Opens New Window Privacy Policy Opens New Window Accessibility Opens New Window Facebook. Opens New Window X. Opens New Window YouTube. Opens New Window Linkedin. Opens New Window Instagram. Opens New Window TikTok. Opens New Window Copyright 2026-2027 Northeastern University Back to top Close this window Print Options Send Page to Printer Print this page. Download Page (PDF)The PDF will include all information unique to this page. var consentListeners=[];window.addConsentListenerTA=function(b){consentListeners.push(b)};var onConsentChange=function(b,a){consentListeners.forEach(function(d){d(b,a)})},__dispatched__={},__i__=self.postMessage&&setInterval(function(){if(self.PrivacyManagerAPI&&__i__){var b={PrivacyManagerAPI:{action:"getConsentDecision",timestamp:(new Date).getTime(),self:self.location.host}};self.top.postMessage(JSON.stringify(b),"*");__i__=clearInterval(__i__)}},50); self.addEventListener("message",function(b,a){try{if(b.data&&(a=JSON.parse(b.data))&&(a=a.PrivacyManagerAPI)&&a.capabilities&&a.action=="getConsentDecision"){console.log("On consent changed!");var d=window.truste.util.readCookie("notice_behavior")||truste.eu.bindMap.behavior+","+truste.eu.bindMap.behaviorManager,f=window.truste.util.readCookie("cmapi_cookie_privacy")||"";onConsentChange(f,d);self.dataLayer&&self.dataLayer.push({event:"Consent Changed"});console.log("After On consent changed!")}if(b.data&& (a=JSON.parse(b.data))&&(a=a.PrivacyManagerAPI)&&a.capabilities&&a.action=="getConsentDecision"){var e=self.PrivacyManagerAPI.callApi("getGDPRConsentDecision",self.location.host).consentDecision;e&&e.forEach(function(c){__dispatched__[c]||(self.dataLayer&&self.dataLayer.push({event:"GDPR Pref Allows "+c}),__dispatched__[c]=1)})}}catch(c){}}); (function(a){"function"===typeof TTDUniversalPixelApi&&(a=new TTDUniversalPixelApi,a.init("gx2pmp9",["fig9091"],"https://insight.adsrvr.org/track/up","ttdUniversalPixelTag9ab70611d0784a53bffadad380ec3a95"))})(this); (function(a){"function"===typeof TTDUniversalPixelApi&&(a=new TTDUniversalPixelApi,a.init("gx2pmp9",["nddbe15"],"https://insight.adsrvr.org/track/up","ttdUniversalPixelTag6f27e0d83ee647de8696f2ef49bc29d2"))})(this); function createCookie(c,b){if(b){var a=new Date;a.setTime(a.getTime()+864E5);a="; expires\x3d"+a.toGMTString();var d="domain\x3d"+(document.domain.match(/[^\.]*\.[^.]*$/)||[""])[0]+";",e="SameSite\x3dNone; Secure";document.cookie=c+"\x3d"+b+a+"; path\x3d/;"+d+e}}createCookie("utm_source",google_tag_manager["rm"]["758267"](8));createCookie("utm_medium",google_tag_manager["rm"]["758267"](9));createCookie("utm_campaign",google_tag_manager["rm"]["758267"](10));createCookie("utm_content",google_tag_manager["rm"]["758267"](11));createCookie("utm_term",google_tag_manager["rm"]["758267"](12)); createCookie("utm_mktoid",google_tag_manager["rm"]["758267"](13));createCookie("nu_clientid",google_tag_manager["rm"]["758267"](14));createCookie("nu_gclid",google_tag_manager["rm"]["758267"](15));var _STATE={}; function runOnce(){!_STATE.hasRunOnce&&window.truste&&truste.eu&&truste.eu.prefclose&&(console.log("doing run once"),_STATE.oldValue=truste.eu.bindMap.prefCookie&&truste.eu.bindMap.prefCookie.split(":")[0].replace(/[^\d.]/g,"-"),_STATE.oldMethod=truste.eu.prefclose,truste.eu.prefclose=function(){_STATE.oldMethod();truste.eu.bindMap.prefCookie&&truste.eu.bindMap.prefCookie.split(":")[0].replace(/[^\d.]/g,"-")!==_STATE.oldValue&&setTimeout(function(){window.location.reload()},20)},_STATE.hasRunOnce=!0, _STATE.i&&clearInterval(_STATE.i))}_STATE.i=setInterval(runOnce,10);document.body.addEventListener("click",function(a){a&&a.target&&a.target.id==="truste-consent-button"&&setTimeout(function(){window.location.reload()},1E3)});(function(){function b(){(window.dataLayer=window.dataLayer||[]).push({event:"lead_form_view"})}if(window.MutationObserver){var c='[id^\x3d"form_"][id$\x3d"_container"]';try{if(document.querySelector(c))b();else{var a=new MutationObserver(function(){document.querySelector(c)&&(b(),a.disconnect())});a.observe(document.documentElement,{childList:!0,subtree:!0});setTimeout(function(){a.disconnect()},1E4)}}catch(d){}}})();
Subject
BIOT
Credits (min)
1
Credits (max)
4
Credit unit
Hours
Type
course
Repeatable
May be repeated five times for a maximum of 6 total semester hours.
