15 courses with the subject CHEM GU, each shown exactly as we captured it from the college's catalog, with every element we hold. Where the wording looks broken, that is our reading of the catalog, not the college's text.
CHEM GU4071INORGANIC CHEMISTRY4.50
Prerequisites: (CHEM UN1403 and CHEM UN1404) or (CHEM UN1604) or (CHEM UN2045 and CHEM UN2046) Prerequisites: (CHEM UN1403 and CHEM UN1404) or (CHEM UN1604) or (CHEM UN2045 and CHEM UN2046) , or the equivalent. Principles governing the structure and reactivity of inorganic compounds surveyed from experimental and theoretical viewpoints. Topics include inorganic solids, aqueous and nonaqueous solutions, the chemistry of selected main group elements, transition metal chemistry, metal clusters, metal carbonyls, and organometallic chemistry, bonding and resonance, symmetry and molecular orbitals, and spectroscopy
Prerequisites: organic chemistry and biology courses, neuroscience or neurobiology recommended, but not required. Prerequisites: Organic chemistry and biology courses, neuroscience or neurobiology recommended, but not required. The study of the brain is one of the most exciting frontiers in science and medicine today. Although neuroscience is by nature a multi-disciplinary effort, chemistry has played many critical roles in the development of modern neuroscience, neuropharmacology, and brain imaging. Chemistry, and the chemical probes it generates, such as molecular modulators, therapeutics, imaging agents, sensors, or actuators, will continue to impact neuroscience on both preclinical and clinical levels. In this course, two major themes will be discussed. In the first one, titled Imaging brain function with chemical tools, we will discuss molecular designs and functional parameters of widely used fluorescent sensors in neuroscience (calcium, voltage, and neurotransmitter sensors), their impact on neuroscience, pros and cons of genetically encoded sensors versus chemical probes, and translatability of these approaches to the human brain. In the second major theme, titled Perturbation of the brain function with chemical tools, we will examine psychoactive substances, the basics of medicinal chemistry, brain receptor activation mechanisms and coupled signaling pathways, and their effects on circuit and brain function. We will also discuss recent approaches, failures and successes in the treatment of neurodegenerative and psychiatric disorders. Recent advances in precise brain function perturbation by light (optogenetics and photopharmacology) will also be introduced. In the context of both themes we will discuss the current and future possibilities for the design of novel materials, drawing on the wide molecular structural space (small molecules, proteins, polymers, nanomaterials), aimed at monitoring, modulating, and repairing human brain function. This course is intended for students (undergraduate and graduate) from the science, engineering and medical departments
Prerequisites: (CHEM UN2443 and CHEM UN2444) elementary organic chemistry. (Some background in inorganic and physical chemistry is helpful but not required.)
CHEM GU4104STRUCTURAL METHODS IN INORGANIC CHEMISTR2.50
The determination of structures by diffraction methods, focusing on single crystal X-ray diffraction, is described. Emphasis is placed on a critical evaluation of published data.
CHEM GU4111APPLICATIONS OF NMR SPECTROSCOPY TO INOR2.50
The use of multinuclear NMR spectroscopy in the determination of the structures of inorganic molecules and the use of dynamic NMR spectroscopy (variable temperature NMR and magnetization transfer techniques) to provide information concerned with reaction mechanisms
Prerequisites: elementary organic chemistry. Prerequisites: elementary organic chemistry. Introduction to theory and practice of NMR spectroscopy. Instrumental aspects, basic NMR theory, NOE, and a survey of 2D methods are covered
Prerequisites: elementary organic and physical chemistry. Prerequisites: elementary organic and physical chemistry. The mechanisms of organic reactions, structure of organic molecules, and theories of reactivity. How reactive intermediates are recognized and mechanisms are deduced using kinetics, stereochemistry, isotopes, and physical measurements
This course is intended for graduate students and advanced undergraduate students. The main purpose of the course is to introduce students to modern synthetic chemistry via the selected series of topics (synthetic planning and the logic of organic assembly, classical and new reactions/methods and their use in complex target synthesis). Mechanistic underpinning of the discussed reaction processes will also be briefly discussed. For each module (see the content below), specific examples of syntheses of natural products and/or synthetic materials will be provided. In addition to lectures by Prof. Sames, students will select and present relevant papers in the class (the number of student symposia will depend on the final enrollment in this course). The basic knowledge of transition metal chemistry is recommended for the cross-coupling reactions (i.e. structure, electron counting, and elemental reaction types of transition metals)
CHEM GU4149Total Synthesis of Natural Products4.00
This course covers the reactions, strategies, and tactics needed to tackle the molecular complexity posed by the structures of complex natural products. Building upon reactions learned in synthetic methods, additional examples of modern methods for bond-forming reactions will be presented, as will the tools necessary to logically analyze and build complex molecular targets. Primary literature sources will be emphasized. You may be asked to serve as research subjects in studies under the direction of the faculty while enrolled in this course. Participation is voluntary
Prerequisites: elementary physical chemistry. Basic quantum mechanics: the Schrodinger equation and its interpretation, exact solutions in simple cases, methods or approximations including time-independent and time-dependent perturbation theory, spin and orbital angular momentum, spin-spin interactions, and an introduction to atomic and molecular structure
Prerequisites: elementary physical chemistry. Corequisites: CHEM G4221. Topics include the classical and quantum statistical mechanics of gases, liquids, and solids
Molecular modeling has become an integral part of research in many areas of chemistry, and in industry in drug discovery and materials design. Many experimental papers in the literature are routinely complemented by molecular modeling calculations. Experimental scientists working in industry have a significant advantage if they know how to optimally use modeling software. The course would consist of a normal lecture part plus a lab session every week in which the students learn to use modeling software by working on projects.
Prerequisites: (CHEM UN2443 and CHEM UN2444) and (CHEM UN3079 and CHEM UN3080) and (BIOC UN3501) elementary organic chemistry CHEM W3443-CHEM W3444. Recommended preparation: elementary physical chemistry CHEM W3079-CHEM W3080 and biochemistry BIOC C3501. Prerequisites: (CHEM UN2443 and CHEM UN2444) and (CHEM UN3079 and CHEM UN3080) and (BIOC UN3501) , or the equivalent. Development and application of chemical methods for understanding the molecular mechanisms of cellular processes. Review of the biosynthesis, chemical synthesis, and structure and function of proteins and nucleic acids. Application of chemical methods--including structural biology, enzymology, chemical genetics, and the synthesis of modified biological molecules--to the study of cellular processes--including transcription, translation, and signal transduction
The goal of this course is to explore how chemical methods and concepts have impacted our ability to understand and manipulate protein structure and function. We will navigate this subject through a combination of lectures and structured discussions on research articles from the literature. The course is divided into three segments: (1) In the first part, we will review the rudiments of protein structure and function, then delve into various aspects of enzyme chemistry and polypeptide biosynthesis. (2) In the second part of the course, we will cover synthetic methods to produce and chemically modify peptides and proteins. (3) In the final part, we will discuss chemical approaches to control protein function and monitor protein activity, focusing on methods that use small molecules and mass spectrometry proteomics
Spring 2026: CHEM GU4324 Course Number Section/Call Number Times/Location Instructor Points Enrollment CHEM 4324 001/11517 T F 4:10pm - 5:25pm 320 Havemeyer Hall Ann McDermott 4.50 5/25
