University of North Carolina at Chapel Hill · Courses
GNET
38 courses with the subject GNET, each shown exactly as we captured it from the college's catalog, with every element we hold. Where the wording looks broken, that is our reading of the catalog, not the college's text.
GNET 603MiBio Seminar2
This class is designed to 1) enhance students' ability to present scientific material to their peers in a comprehensive, cohesive manner, 2) familiarize students with scientific concepts and technologies used in multiple disciplines, 3) expose students to cutting edge research, 4) prepare students to gain substantial meaning from seminars and to ask questions, and 5) enhance students' ability to evaluate scientific papers and seminars.
Permission of the instructor. Presentations of current research or relevant papers from the literature on development by students will be followed by open forum discussion of relevant points, and critique of presentation skills. Two hours per week.
Permission of the instructor for undergraduates. Genetic and molecular control of plant and animal development. Extensive reading from primary literature.
This course explores cutting edge research in molecular biology -- the investigation at molecule-scale of the mechanisms behind life. We briefly review core-principles in molecular biology, then investigate more recent research that extends or overturns these core principles.
Required preparation for undergraduates, at least one undergraduate course in both biochemistry and genetics. The purpose of this course is to provide historical, basic, and current information about the flow and regulation of genetic information from DNA to RNA in a variety of biological systems. Three lecture hours a week.
GNET 635Clinical and Counseling Aspects of Human Genetics3
Topics in clinical genetics including pedigree analysis, counseling/ethical issues, genetic testing, screening, and issues in human research. Taught in a small group format. Active student participation is expected.
Students will learn about various topics that form the basis for understanding quantitative genetics of complex traits with biomedical and agricultural relevance. The ultimate goal of quantitative genetics in this postgenomic era is prediction of phenotype from genotype, namely deducing the molecular basis for genetic trait variation.
This course will focus on the laboratory mouse as a model organism to learn fundamental genetic concepts and understand how state-of-the-art experimental approaches are being used to elucidate gene function and the genetic architecture of biological traits.
The course covers principles and modern approaches of human genetics and genomics, including human genetic variation, linkage, genome-wide association analysis, sequencing for variant discovery in monogenic and complex diseases, regulatory variation, the molecular basis of human disease, and functional validation of disease variants.
This course will provide an overview of methods in human genetics during the critical reading of selected literature and work of speakers that will present in the Friday Seminar Series.
Permission of the instructor. This course will provide an overview of the use of the mouse as an experimental model for determining factors, both genetic and environmental, that contribute to human diseases. One seminar hour a week.
Required of all candidates for the degree in genetics. A course to provide public lecture experience to advanced genetics students. Students present personal research seminars based on their individual dissertation projects. Lectures are privately critiqued by fellow students and genetics faculty.
Required of all candidates for the degree in genetics. A course to provide public lecture experience to advanced genetics students. Students present personal research seminars based on their individual dissertation projects. Lectures are privately critiqued by fellow students and genetics faculty.
This short course will cover methods of inferring/estimating natural selection, including the Dn/Ds ratio, the McDonald-Kreitman test, and the Poisson Random Field model. The course will feature discussions of high-profile publications that describe the application of these methods to yield insights into the forces that have shaped organismal evolution.
GNET 730Fundamentals of Quantitative Image Analysis for Light Microscopy1
This course is a practical introduction to quantitative analysis of light microscopy images. During the class students will follow tutorials that will guide them through common tasks in analysis of biological images. They will be introduced to basic concepts of image processing like image registration, filtering, object detection etc.
GNET 742Introduction to UNIX/LINUX for Biomedical Researchers1
This module will introduce the natural environment of bioinformatics: the Unix/Linux command line. Material will cover logging into remote machines, filesystem organization and file manipulation, installing and using software (including bioinformatic examples such as HMMER and BLAST). Module will use UNC's Longleaf computing cluster, learning how to manage pre-configured software environments, batch and interactive job submission, and briefly review Longleaf OnDemand-available computational environments RStudio and Jupyter.
GNET 743Introductory Statistical Analysis in R for Biomedical Scientists1
This module will introduce the data analysis environment R and use it to illustrate basic concepts in data manipulation, plotting of complex data, and basic statistical modeling. Class examples will be general and will aim to build familiarity and confidence with R and data analysis.
GNET 744Biological Sequence Analysis, Protein-Structure, and Genome-Wide Data2
This module provides an introduction to basic protein structure/function analyses combining sequence informatics and macromolecular structure. In the second half the focus will switch to analysis of genome-wide datasets and methods used for the analysis of such "big data."
This course is designed to familiarize students with everything needed to run an RNA-Seq experiment. There will be minimal emphasis on theory and heavy focus on practical aspects. There are no formal prerequisites required for this course and no prior experience with UNIX or the command line interface is expected.
Human complex diseases are major focus in human genomics. They have important genetic components, but inheritance is probabilistic and not deterministic. This graduate seminar will cover the main approaches (genome-wide association, next-generation sequencing, and structural variation in case-control and pedigree studies) and current knowledge in the main disease areas.
GNET 760Advanced Topics in CRISPR-Based Genome Engineering:Origins, Applications, and Ethical Considerations1
This graduate-level course is designed to teach students about the origins of CRISPR-Cas genome engineering technology, its applications to research and human health, and the ethical/societal considerations surrounding this powerful technology. Emphasis will be made on recent literature, new applications, discoveries and bioethics. Students interested in taking this class must have taken an advanced Genetics or Molecular Biology course.
GNET 801Critical Thinking in Science: From Hypothesis to Grant Proposal3
This journal club-style discussion course explores the molecular mechanisms regulating normal cell cycle progression and how their deregulation leads to cancer. We will trace the historical development of the cell cycle field, illustrating how scientific inquiry has shaped current paradigms. This course is ideal for students interested in cell proliferation and cancer biology, regardless of prior knowledge.
Required preparation, two courses in genetics. Permission of the instructor. Principles of genetic pedagogy. Students are responsible for assistance in teaching genetics and work under the supervision of the faculty, with whom they have regular discussion of methods, content, and evaluation of performance. (Throughout the year.) Staff.
GNET 865Advanced Nutritional Biochemistry: Nutrigenomics and Precision Nutrition2
Permission of the instructor. Course focuses on nutrigenetics and nutrigenomics with an emphasis on the genetic and dietary interactions predisposing one to increased risk of disease.
Provides practical experience to predoctoral students in writing fellowship proposals, using the NIH F31 as a template. Students will have weekly writing assignments, with feedback given by students and faculty. Open to 2nd and 3rd year students in the Curriculum or by permission of the instructor.
Provides advanced predoctoral students with an understanding of issues relevant to conducting biomedical research as responsible citizens. It fulfills the NIH requirement for continued RCR training. Open to 4th and 5th year students in the Biology, Genetics and Molecular Biology, and Biochemistry PhD programs or by permission of the instructor.
GNET 990Research Practicum/Internship in Bioinformatics and Computational Biology1-9
The Research Practicum/Internship in Bioinformatics and Computational Biology (BCB) is a planned, individualized, mentored, evaluated, experiential learning opportunity that serves as a bridge between academic training and post-training practice. The internship/practicum provides special opportunities for learning that are different from, supplementary to, and supportive of the academic components of the PhD program.
Subject
GNET
Credits (min)
1
Credits (max)
9
Credit unit
Credits
Type
course
Repeatable
May be repeated for credit; may be repeated in the same term for different topics; 9 total credits.
