BIOL

y

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Subject

BIOL

Type

course

Edition

2026

Source

www.college.upenn.edu

lab,1.5 c.u.)

Subject

BIOL

Type

course

Edition

2026

Source

www.college.upenn.edu

This course will examine the ways in which humans manipulate - and have been manipulated by - the organisms we depend on for food, with particular emphasis on the biological factors that influence this interaction. The first part of the course will cover the biology, genetics, evolution, and breeding of cultivated plants and animals; the second part will concern the ecological, economic, and political factors that influence food production. Spring, odd numbered years only 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

1.5 c.u.)

Subject

BIOL

Type

course

Edition

2026

Source

www.college.upenn.edu

to Biology

Subject

BIOL

Credits (min)

1.5

Credits (max)

1.5

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Physical Sciences, Calculus, Statistics, and Computer Science Select 4 course units from the below list 4

Subject

BIOL

Credits (min)

2

Credits (max)

2

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Introduction to the structure and function of the vertebrate nervous system. We begin with the cellular basis of neuronal activities, then discuss the physiological bases of motor control, sensory systems, motivated behaviors, and higher mental processes. This course is intended for students interested in the neurobiology of behavior, ranging from animal behaviors to clinical disorders.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

& BIOL 2610 Biology of Life and Ecology: From individuals to ecosystems If BIOL 1121 & BIOL 2610 are chosen, an additional 1 CU is required. Students may choose any course with Attribute AERL (https://catalog.upenn.edu/attributes/aerl/) Earth & Environmental Science Select 1 upper level course approved by advisor 1 Total Course Units 6 The degree and major requirements displayed are intended as a guide for students entering in the Fall of 2026 and later. Students should consult with their academic program regarding final certifications and 4 requirements for graduation.

Subject

BIOL

Credits (min)

1

Credits (max)

1

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

concurrent with BIOL 1121 Introduction to Biology - The Molecular Biology of Life. 3 course units count as 2 for this major. The degree and major requirements displayed are intended as a guide for students entering in the Fall of 2026 and later. Students should consult with their academic program regarding final certifications and requirements for graduation. Sample Plan of Study Course Title Co

Subject

BIOL

Credits (min)

3

Credits (max)

3

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Track 2 (3 course units):

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Biology of Life (lecture and recitation, 1.0 c.u.)

Subject

BIOL

Type

course

Edition

2026

Source

www.college.upenn.edu

only, 0.5 c.u.)

Subject

BIOL

Type

course

Edition

2026

Source

www.college.upenn.edu

with one hour lecture, 0.5 c.u.) * NOTE: BIOL 121 and 123 must be taken concurrently. Track 2 Recommended for students with one year of high school biology. Introductory level:

Subject

BIOL

Type

course

Edition

2026

Source

www.college.upenn.edu

Intensive exposure to current issues and solutions in contemporary human interactions with the environment. Global in scope, but focused on case histories. Emphasis on providing biological and sociological background for a given major environment-human interaction, and state- of-the-art suggested solutions.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Tropical marine ecology explores the diversity and function of tropical marine organisms and ecosystems. Students will learn about the composition and functions of various coastal and marine ecosystems found in the tropics, including coral reefs, seagrass meadows, mangroves, salt marshes, and tidepools. A major focus of this course will be on coral reefs, which are among the most biodiverse and productive ecosystems in the ocean. The course will also explore the physical and biological processes that shape life in tropical marine ecosystems, as well as how these ecosystems both support and are affected by human activities from the local to global level. Weekly lectures will provide a background overview of each topic and will be followed by small group discussions that explore a subject in depth. Finally, students will have the opportunity to explore the intersection of their own interests and background with tropical marine ecology by developing an oral presentation and research paper on a topic of their choosing. The classroom component will be complemented by a field expedition to the island of Bermuda, where students will observe these tropical marine ecosystems firsthand and compare the biodiversity of the flora and fauna across the many different coastal and marine habitats of Bermuda. While in Bermuda, students will also participate in restoration activities to help protect native species and visit cultural sites that explore the link between the marine ecosystems of the island and the economy and culture of the local community. Fall, even numbered years only 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Independent study for students doing research based on data that is generated in a clinical setting. Projects must be sponsored by standing faculty of the University of Pennsylvania and co-sponsored by a faculty member in the Department of Biology. The project must be of biological interest and must use appropriate quantitative or statistical methods. A final paper is required. Apply at the Academic Office, 102 Leidy Labs.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

University of Pennsylvania Catalog 319 1 BIOL 2201 Essentials of Molecular Biology and .5 Genetics .5 BIOL 2301 Essentials of Vertebrate Physiology 1.5 BIOL 2701 Elements of Microbiology

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

or BIOL 4010 Advanced Cell Biology

Subject

BIOL

Credits (min)

1

Credits (max)

1

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Group 4:

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

The evolution of behavior in animals will be explored using basic genetic and evolutionary principles. Lectures will highlight behavioral principles using a wide range of animal species, both vertebrate and invertebrate. Examples of behavior include the complex economic decisions related to foraging, migratory birds using geomagnetic fields to find breeding grounds, and the decision individuals make to live in groups. Group living has led to the evolution of social behavior and much of the course will focus on group formation, cooperation among kin, mating systems, territoriality and communication.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will survey the discipline of molecular genetics. Mendelian and molecular genetics will be discussed as well as the use of genetic analysis to address questions in all areas of biology. The processes of DNA replication, transcription, and translation will be discussed at the molecular level. Other topics include the regulation of gene expression and genomics. This course is open to students in the College of Liberal and Professional Studies only.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Group 3:

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

A comparative and quantitative approach to the physiological function of vertebrates. Topics include muscles, nervous system, cardiovascular system, respiration, and renal function. This course is open to students i the College of Liberal and Professional Studies only.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course examines the physiological mechanisms underlying homeostasis in humans. Integration from the cellular to organismal level as well as cooperation of multiple organ systems will be explored. Examples of pathophysiology during disease states will be discussed and highlighted. Although the focus will be on humans, we will study comparative aspects from other vertebrate and non-vertebrate organisms.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Theories and mechanisms of evolution, with emphasis on the genetic basis of evolutionary change.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Introductory probability theory. Principles of statistical methods. Problems of estimation and hypothesis testing in biology and related areas.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Additional Biology/Biology-Related Requirement Select 6 additional course units of Biology with: Attribute: ABB2 (https://catalog.upenn.edu/attributes/ abb2/) Attribute: ABXD (https://catalog.upenn.edu/attributes/ abxd/) Attribute: ABAM (https://catalog.upenn.edu/attributes/ abam/) Attribute: ABCM (https://catalog.upenn.edu/attributes/ abcm/) Attribute: ABAN (https://catalog.upenn.edu/attributes/ aban/) Attribute: ABCB (https://catalog.upenn.edu/attributes/ abcb/) Attribute: ABEE (https://catalog.upenn.edu/attributes/ abee/) Attribute: ABGD (https://catalog.upenn.edu/attributes/ abgd/) Attribute: ABGG (https://catalog.upenn.edu/attributes/ abgg/) Attribute: ABMD (https://catalog.upenn.edu/attributes/ abmd/) Attribute: ABMI (https://catalog.upenn.edu/attributes/ abmi/) Attribute: ABMC (https://catalog.upenn.edu/attributes/ abmc/) Or, BIOL courses 2000-5999 except courses specifically for LPS (BIOL 2001, 2201, 2301, 2701, 2801, 3004, 3006, and 3313). Three of them may be other Biology related courses

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Microbiology plays a central role in diverse areas of human life such as infectious disease, ecology, and biotechnology. This course will cover aspects of modern microbiology with an emphasis on prokaryotic organisms. The topics will include basic aspects of microbial diversity, genetics, and pathogenesis as well as examples of applied microbiology. This course is open to students in the College of Liberal and Professional Studies only.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

*Biochemistry is required for most students

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

1 Required Nutrition Science Courses 1 NURS 1120 Nutrition: Science & Applications 1

Subject

BIOL

Credits (min)

1

Credits (max)

1

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course focuses on selected topics concerning infectious agents, the diseases they cause in humans, and the social and scientific challenges they pose. The first section addresses the principles of epidemiology and microbial pathogenesis, as well as pathophysiology of infectious diseases. In the second section, tools and techniques of diagnosis, tracking, and control of infectious diseases will be discussed. To develo a broad understanding of the many different aspects of infectious processes, selected viral, fungal, protozoan, and helminthic pathogens and related infectious diseases will be presented. This course is open to students in the College of Liberal and Professional Studies only.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed to introduce the undergraduate student to the structure of tissues at the cellular level and to the way in which those tissues are assembled into organs. This knowledge of structure will be the basis for discussion of tissue and organ function. This course is ope to students in the College of Liberal and Professional Studies only.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Asymmetric cell division (ACD) is a fundamental biological process through which a single cell generates two daughters with distinct identities, behaviors, or developmental potentials. This course examines the molecular, cellular, and physical mechanisms that produce asymmetry during cell division, and development with particular p emphasis on when and how asymmetric inheritance actually determines cell fate, and when it does not. Using experimental systems spanning embryos, neural stem cells, germline stem cells, students will analyze how polarity, spindle orientation, fate determinant segregation, organelle inheritance, epigenetic asymmetry, and niche signaling interact to control development, tissue maintenance, and regeneration in plants and animals. A central theme of the course is the distinction between asymmetric inheritance and asymmetric fate specification, a distinction that has important implications for disease and agriculture. While many stem and progenitor cells exhibit unequal inheritance of cellular components, only a limited number of systems use intrinsic asymmetry as a deterministic fate-specifying mechanism. In most adult tissues, fate is specified extrinsically by position, signaling environment, or n tissue architecture. Through critical analysis of primary and secondary literature, students will learn how failures in these regulatory systems contribute to disease, including cancer, neurodevelopmental disorders, and tissue degeneration, where disrupted polarity, spindle orientation, or asymmetric division can lead to inappropriate self-renewal or loss of differentiation. Throughout the course, students will integrate theory with empirical evidence, focusing on experimental logic, figure interpretation, and causal inference. Topics include cortical polarity networks, spindle positioning and mechanics, fate determinant localization and anchoring, centrosome and organelle asymmetry, immortal strand and epigenetic inheritance hypotheses, and the role of the stem cell niche. Students will evaluate classic and modern experiments, assess technical and conceptual limitations, and distinguish well-supported mechanisms from debated or correlative models. By the end of the course, students will be able to explain how asymmetric cell division operates across biological systems, articulate why true intrinsic fate determinism is rare, and evaluate how layered asymmetries contribute to robustness, tissue homeostasis, and organismal health. The course prepares students for advanced study or research in cell biology, developmental biology, genetics, medicine, and plant and agricultural sciences by emphasizing mechanistic reasoning and evidence-based interpretation of the primary literature. Fall, even numbered years only 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Prerequisite

BIOL 2210 AND BIOL 2010

A view of how an animal embryo is specified to develop and differentiate into a wide spectrum of cell types, and how the spatial patterns and axes of embyros are determined. The course will focus on genetic and molecular approaches, but will also cover the comparative anatomy of developing embryos to the extent necessary to understand the conserved aspects of embryonic patterning. Special emphasis will be placed on organisms with particular advantages for the study of embryonic development: e.g., mouse, frog, zebrafish, and Drosophila. The first half of the course will cover cell fate restrictions, cloning animals using nuclear transfer, stem cell biology, formation of the embryonic axes in vertebrates and Drosophila, and patterning of the neural tube and mesodermal tissues. The second half of the course will focus on emerging ideas and findings in the field, with emphasis on analysis of original literature.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

General Electives (including Ethics and Writing) Select 2 Social Science courses Social Science (EUSS) (https://catalog.upenn.edu/ attributes/euss/) Select 2 Humanities courses Humanities (EUHS) (https://catalog.upenn.edu/attributes/ euhs/) Select 1 Social Science or Humanities course Social Science (EUSS) (https://catalog.upenn.edu/ attributes/euss/) Humanities (EUHS) (https://catalog.upenn.edu/attributes/ euhs/) Select 1 Social Science, Humanities, or Technology in Business & Society course Social Science (EUSS) (https://catalog.upenn.edu/ attributes/euss/) Humanities (EUHS) (https://catalog.upenn.edu/attributes/ euhs/) Technology in Business and Society (EUTB) (https:// catalog.upenn.edu/attributes/eutb/)

Subject

BIOL

Credits (min)

2

Credits (max)

2

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

12 BIOL 4004 Immunobiology

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

An introduction to marine biology and oceanography. Topics will include chemical and physical oceanography, a survey of form, function and phylogeny of algae, invertebrates and vertebrates, and an examination of ecological and evolutionary principles as applied to marine organisms and ecosystems.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will focus on plants and climate change in the urban setting, specifically the city of Philadelphia. We will examine the role of plants in urban food, ancestral traditions, community, health & wellbeing, also the ecosystems benefits of plants. We will explore challenges faced by plants and ecosystems due to environmental changes, land use change, and differential access to green spaces. We will discuss plant biological, genetic, breeding, and ecological solutions for enhancing plant resilience. Students will gain hands-on experience, engage in dialog with farm, garden and ecosystem practitioners, as well as city officials and other support systems, NGOs and small businesses. Dialog will occur both on visits to local gardens, farms, or parks with representatives and stakeholders or on campus with guest speakers and each other. Students will develop project ideas, educational materials, plans, or designs that detail possible solutions to problems identified during their investigations. Activities will intersect with to those of PlantARC https:// web.sas.upenn.edu/plantarc/

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Microbiology plays a central role in diverse areas of human life such as infectious disease, ecology, and biotechnology. This course will cover aspects of modern microbiology with an emphasis on prokaryotic organisms. The topics will include basic aspects of microbial diversity, genetics, virology, and pathogenesis as well as examples of applied microbiology.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This laboratory course provides students with a robust microbiological skill set while also giving an opportunity to participate in an authentic research project that may lead to novel antimicrobial discoveries. In the first half of the class students will be given a set of unknown bacteria to identify using biochemical and genetic analysis. Basic and advanced skills in handling bacteria will be learned here. The unknown project will culminate with an in-class presentation. The second half of the course will be an independent research project using soil samples and focused on developing scientific skills. The soil independent project will end in a poster presentation to the class. Microbiological skills will be taught but it will be assumed that you have had an introductory level biological lab experience.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course uses a biological foundation to explore general issues at the interface of biology and society. We will use both historical and contemporary reading materials, with an emphasis on the primary scientific literature, to inform discussions on often controversial issues in biology as well as the social responsibility of scientists to respond to these issues. The course will cover how science has shaped social and political opinions on such topics as race, ethnicity, and gender, as well as how society and politics are influenced by and impact science. This course will provide a background and context in which to consider, anticipate, and respond to biology's present and future ethical and social implications.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Laboratory research with a faculty member in the Department of Biology. Research may also be conducted elsewhere on campus but co-sponsored by a faculty member in Biology. A final paper is required. Apply at the Biology Academic Office, 102 Leidy Labs.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Early development of microbiology, pathology, and immunobiology; molecular and cellular bases of immune phenomena including: immunity to pathogens, immune diseases, autoimmunity, and hypersensitivity. This course is open to students in the College of Liberal and Professional Studies only.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will focus on the molecular mechanisms by which fundamental cellular processes are disrupted in the development of cancer.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for beginning graduate students and advanced undergraduates with a particular enthusiasm for cell biology. Biology 4010 does not attempt to cover all aspects of cell biology, and is therefore not appropriate for students seeking a lecture course which provides a comprehensive survey of the field. Rather, the primary objective of this course is to teach those students considering a career in the biomedical sciences how to read, discuss, and question original research papers effectively. Intensive classroom discussions focus on the experimental methods used, results obtained, interpretation of these results in the context of cell structure and function, and implications for further studies.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for advanced undergraduates and beginning graduate students with a particular interest in infectious disease biology. Note that this course is not a comprehensive survey of the field and is not appropriate for students seeking a lecture course on disease. The primary objective of this course is to teach students considering a career in the biomedical sciences how to read, discuss, and question research papers effectively. Intensive classroom discussions focus on the experimental methods used, results obtained, interpretation of these results in the context of pathogen interactions with host cells and organisms, and implications for basic research and therapeutic development.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Cytoskeleton and cell motility plays a crucial role in many aspects of normal and pathological physiology of individual cells, tissues, and whole organisms, including morphogenesis, immune response, wound healing, oncogenesis, and infection. This course will cover current topics in cell biology with emphasis on cytoskeleton and cell motility and their roles in these processes. Lectures, student presentations, and discussions in the class will be based on primary scientific literature.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Life depends on the propagation of genetic material from one generation to next through cycles of genome replication and cell division. We will focus on chromosomes as discrete entities, rather than collections of genes, that are inherited between cell cycles and across generations. By reading selected primary literature covering several decades, we will build an understanding based on key experiments and insights, focusing on chromosomes and their associated molecular machinery. Topics may include kinetochores and microtubule dynamics, centromeres, the mitotic checkpoint, chromosomal instability and cancer, genetic conflict, chromosome evolution, and artificial chromosomes.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

2026-27 Catalog | Generated 08/03/26

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

A fundamental goal of neuroscience is to understand how neural circuits in the brain function to influence behavior. The aim of this course is to highlight the neural basis of behavior and discuss modern approaches and novel methods to study the neuronal control of classically studied aspects of behavior. Through a combination of discussions, student presentations, and interactive lectures, we will explore the neural systems that regulate the interactions an animal has with the external world. We will explore sensory systems (such as vision, taste, and olfaction), motor systems, and survival behaviors (such as feeding, drinking, mating, and aggression). The course evaluation will be based largely on written work, participation, and presentations.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Animals display extraordinary diversity in their morphology, physiology, and behavior. Traditionally, these topics have been mostly studied from an ecological perspective. This course will focus on recent advances and discoveries that address the underlying biological mechanisms of animal diversity. Specific topics will include the genetic, molecular, and developmental basis of animal morphological diversity, and genetic, molecular, and neural basis of animal behavioral diversity. Students will gain an understanding of how animal diversity is encoded at the different levels of biological organization. The course will be comprised of lectures to introduce topics, discussion of primary literature, and in-class activities.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course focuses on the current state of our knowledge about the neurobiological basis of learning and memory. A combination of lectures and student seminars will explore the molecular and cellular basis of learning in invertebrates and vertebrates from a behavioral and neural perspective.FallAlso Offered As: NRSC 4442, PSYC 3301Prerequisite: BIOL 21101 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

or BE 5690 Principles and Engineering of Cell Signaling or BE 4800 Introduction to Biomedical Imaging or BE 3060 Cellular Engineering

Subject

BIOL

Credits (min)

1

Credits (max)

1

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

shape modern genomes This class explores the evolutionary battles that play out between genes within and across genomes. Pathogens evolve their molecular arsenal to manipulate host cells and enhance their own replication. The host genome fights back with molecular defense mechanisms that evade or suppress the invading bacterial and viral pathogens. Such “molecular arms races” also play out between host genomes and genomic parasites called selfish genetic elements. These selfish elements, like transposons, spore killers, and meiotic drivers, similarly evolve to replicate in their host genomes and the host genome evolves to block proliferation and mitigate the collateral damage. Finally, conflicts over access to mates drives genetic innovations. We will learn about these molecular arms races using the primary literature. During our course meetings, we will discuss assigned articles and engage in small groups around multiple writing assignments. Presentation preparation and writing are two skills that we’ll develop over the semester.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course investigates epigenetic phenomena: heritable alternate states of gene activity that do not result from an alteration in nucleotide composition (mutations). Epigenetic mechanisms regulate genome accessibility and cell differentiation. They play a key role in normal development and in oncogenesis. For example both mammalian X- chromosome inactivation and nuclear transfer (cloning) are subject to epigenetic regulation. Amongst the epigenetic mechanisms we will discuss in this course are chromatin organization, histone modification, DNA methylation and non-coding RNAs. The course is geared toward advanced undergraduate and beginning graduate students and is a combination of lectures, student presentations and research presentations by guest speakers. Students will work with the current scientific literature.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Epigenetic alterations encompass heritable, non-genetic changes to chromatin (the polymer of DNA plus histone proteins) that influence cellular and organismal processes. This course will examine epigenetic mechanisms in directing development from the earliest stages of growth, and in maintaining normal cellular homeostasis during life. We will also explore how diverse epigenetic processes are at the heart of numerous human disease states. We will review topics ranging from an historical perspective of the discovery of epigenetic mechanisms to the use of modern technology and drug development to target epigenetic mechanisms to increase healthy lifespan and combat human disease. The course will involve a combination of didactic lectures, primary scientific literature and research lectures, and student-led presentations. Spring, odd numbered years only Also Offered As: CAMB 4930, GCB 4930 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Prerequisite

BIOL 2210

Development is the process by which organisms grow and acquire their final shape. This remarkably complex process requires exquisite spatiotemporal control, and principles of developmental biology have implications for nearly all other biological disciplines. This course is a deep dive into these general biological principles, using plants as a model system. Students will prepare presentations on primary literature and engage in vigorous discussions in a "journal club" format. Our goal is to learn how developmentally significant genes and cellular interactions control differentiation and pattern formation.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will focus on the molecular basis of neurological diseases, exploring in detail key papers that cover topics including defining the disease genes, development of animal models that provide mechanistic insight, and seminal findings that reveal molecular understanding. Diseases covered will include neurological diseases of great focus today such as Alzheimer's, Fragile-X and autism, dementia, motor neuron degeneration, and microsatellite repeat expansion disorders. The course will provide a perspective from initial molecular determination through current status. Students will gain an understanding of how the molecular basis of a disease is discovered (from classical genetics to modern genomics) and how such diseases can be modeled in simple genetic systems for mechanistic insight. The course will be comprised of lectures with detailed analysis of primary literature and in-class activities. Gradin will be based on class participation, exams, and written papers. Biology 2210 is a pre-requisite. Seniors are prioritized for the course

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for advanced undergraduate and graduate students who are interested in molecular physiology of sensory signal transduction. The major topics to cover will be signal transduction mechanisms used by membrane ion channels and receptors that detect the sensory stimuli (light, sound, temperature, smell and taste, for example) and transmit the signals to the nervous system. Modern molecular, genetic and structural techniques (electrophysiology, protein structural determination/analysis, animal genetics, and human disease, for example) will be introduced along with each topic. References will be primary research articles. Students will critically evaluate research discoveries through analysis of research papers. Each student will deliver two presentations and write a 10-page research proposal.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for students who are interested in understanding how physiological functions are achieved. Taking advantage of the recent explosion in genetic data and high-resolution protein structure analysis across organisms, the course focuses on the evolution of physiological functions at the genetic, structural, circuit and organismal levels. Examples include the co-evolution of toxins and toxin resistance between hunter and prey, the evolution of substance transport across cell membranes, intracellular signaling cascades, intercellular communication, distributed and centralized nervous systems, neural circuits controlling physiological functions such as feeding, locomotion and visual information processing. Students are expected to learn 1) basic physiological processes, their origin and adaptation, 2) modern genetic, structural and physiological techniques, 3) to critically evaluate research findings, 4) to present scientific papers, and 5) to write a research report.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

the muscular system The course will focus on muscle function from the level of molecules to whole animal locomotion. At each level of organization, muscle function will be explored from mechanical and energetic viewpoints. The course will include lectures, demonstrations, and several guest expert lectures. Students will also be introduced to realistic musculo-skeletal modelling and forward dynamic simulations to explore integrated function.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

g This course will focus on fundamental topics related to the ecological and evolutionary processes driving the transmission of pathogenic microbes among hosts including life-history strategies; evolution of pathogenic traits; the impacts of temporal, spatial and host-trait heterogeneity; and factors causing the emergence of an infectious pathogen. Examples will be drawn from human, wildlife, and plant pathogens to illustrate these ecological and evolutionary topics. Students will learn to develop and apply current ecological and evolutionary theory to infectious microbe research and gain practical experience accessing, interpreting and synthesizing the peer-reviewed scientific literature through a combination of popular and scientific readings, discussion, and lecture.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course focuses on the underlying principles, implementation, and interpretation of statistical methods commonly used in biology. Lectures will incorporate exercises that implement these analyses in the open source software R, as well as exercises in data visualization. We will draw on examples from ecology, evolution, genetics, and genomics.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Introduction to basic theoretical tools to study the evolutionary and ecological dynamics of populations. Topics to be discussed include: basic population dynamics and population genetics theory, evolutionary game theory/adaptive dynamics, social evolution (kin selection/multilevel selection), life-history evolution, and stochastic models. Other topics may be added based on the specific interests of students in the class.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

The goal of this course is to develop a deeper understanding of techniques and concepts used in Computational Biology. Both theoretical and practical aspects of a range of methods will be covered. Theoretical aspects will include statistical analysis, modeling, and algorithm design. This course cannot provide a comprehensive survey of the field but focuses on a select core set of topics and data types. We will discuss the genome browser, alignment algorithms, classical and non- parametric statistics, pathway analysis, dimensionality reduction, GWAS, multiple testing and machine learning, with primary focus on biomedical data. UNIX, R and Python will be utilized to learn to execute big data analysis pipelines, including RNA-Seq and DNA-Seq. UNIX and R will be taught from first principles but programming experience in Python is expected. Students without prior experience with Python should consider taking PHYS 1100 before taking this class. You will be provided with a computational (cloud based) platform on which to do all programming and assignments.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course focuses on teaching students the Pennsylvania flora, both native and naturalized. Through weekly field trips, students will gain an appreciation for the diversity of plant species and plant communities in PA, and observe and discuss ecological and historical forces that influence plant species occurrences and plant communities. The ability to quickly and accurately identify plants in the field, through both sight identification and the use of a dichotomous key, is the major thrust of this course. Students will also learn how to appropriately collect plant materials for further study/identification in the laboratory and for archiving in an herbarium collection.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Urban environments present unique challenges and opportunities for plant species. After a review of plant taxonomy and anatomy, this course will examine the ecological impacts of plants in urban settings. We will explore landscapes in and around Penn’s campus to understand how plant communities contribute to ecosystem services in these environments. The applied uses of plants in agriculture, medicine, bioremediation, and other aspects of community health will also be explored.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Deep Time 1

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is a lab/lecture/seminar hybrid that will meet once per week for three hours. Each session will consist of mini-lecture/lab, paper discussions/lab, or solely lab efforts. All reading assignments will be available on Canvas (no textbook fees). We will exam various aspects of photosynthesis, water relations and nutrient acquisition in the context of the evolutionary progression of higher plants. With each subject, we will consider, measure, and in some cases model whole-plant physiology while examining sub-cellular-level controls and ecosystem-to-global- level consequences. This course is designed to give molecular biologists through earth-system scientists the tools to measure and understand whole-plant physiological responses to molecular manipulation and environmental variability. All students will learn to appreciate the context of their work on both micro and macro scales.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This interactive course is intended for a small group of students aspiring to pursue research in microbiology, preferably using prokaryotes. Students will study selected papers and will attend the Prokaryotic Microbiology Seminars on Fridays. Specific problems of importance to a given field at a particular time will be critically analyzed and discussed: How were cutting edge techniques of the time used to address these problems? How would the same problems be approached using current techniques? The emphasis of the course will be on learning to become a thoughtful experimentalist rather than acquiring the hottest emerging knowledge.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will cover research articles from both the classic and contemporary literature on the genetics, cell biology, and physiology of prokaryotes. The material will focus on a small number of subjects in depth, with an emphasis on how the field has arrived at its current state of knowledge and on exciting new research directions. Possible topics include: stress responses, cell signaling, subcellular organization, bacteriophages, microbial communities, and host-microbe interactions. Spring, even numbered years only Mutually Exclusive: BIOL 5720 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Prerequisite

BIOL 2210 OR BIOL 3710

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course provides a thorough interdisciplinary overview of the modern drug discovery and development process. Building on foundational life sciences and molecular science courses, this course demonstrates how basic scientific concepts are applied to real-world challenges in drug discovery and development. The course begins with a history of medicines in society and the evolution of the modern pharmaceutical and biotech industry. It then covers a wide range of topics, including the identification of novel therapeutic targets, the molecular design of safe and effective drugs, considerations related to the final clinical formulations, clinical trial design and execution, regulatory pathways for drug approval, and post-market safety and efficacy monitoring. The curriculum is led by experienced researchers, biotech innovators, and professionals from both academia and the biopharmaceutical industry. It covers essential disciplines that are vital to drug discovery and development. In addition to core subjects such as physiology, cell biology, molecular biology, and biochemistry, the course also explores related fields, including organic chemistry, medicinal chemistry, pharmacology, pharmacokinetics, toxicology, materials science, and biotechnology. Students will also investigate in silico methodologies, explore applications of AI in drug discovery and development, and learn about advanced biomanufacturing processes. By the course's end, students will understand the various challenges, opportunities, and career paths available within drug discovery, the pharmaceutical sector, and the broader biotechnology industry.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Intensive laboratory class where open-ended, interesting biological problems are explored using modern lab techniques. Topics may include protein structure/function studies; genetic screens, genomics and gene expression studies; proteomics and protein purification techniques; and molecular cloning and DNA manipulation. The course emphasizes developing scientific communication and independent research skills. Course topics reflect the interests of individual Biology faculty members. This course is recommended for students considering independent research.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

1 CHEM 2999 Directed Study and Seminar

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for beginning graduate students and advanced undergraduates with a particular enthusiasm for cell biology. Biology 4010/5010 does not attempt to cover all aspects of cell biology, and is therefore not appropriate for students seeking a lecture course which provides a comprehensive survey of the field. Rather, the primary objective of this course is to teach those students considering a career in the biomedical sciences how to read, discuss, and question original research papers effectively. Intensive classroom discussions focus on the experimental methods used, results obtained, interpretation of these results in the context of cell structure and function, and implications for further studies.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for advanced undergraduates and beginning graduate students with a particular interest in infectious disease biology. Note that this course is not a comprehensive survey of the field and is not appropriate for students seeking a lecture course on disease. The primary objective of this course is to teach students considering a career in the biomedical sciences how to read, discuss, and question research papers effectively. Intensive classroom discussions focus on the experimental methods used, results obtained, interpretation of these results in the context of pathogen interactions with host cells and organisms, and implications for basic research and therapeutic development.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

The evolution of multicellularity required that cells be able to both send and receive signals from their neighbors. The development of organs and differentiation of cells and tissues requires reliable and continuous communication between cells. Consequences of inappropriate or anomalous signaling include development abnormalities and cancer. This class will examine mechanisms of cell-to-cell signaling between cells in plants and animals with an emphasis on the cell biology of development.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Cytoskeleton and cell motility plays a crucial role in many aspects of normal and pathological physiology of individual cells, tissues, and whole organisms, including morphogenesis, immune response, wound healing, oncogenesis, and infection. This course will cover current topics in cell biology with emphasis on cytoskeleton and cell motility and their roles in these processes. Lectures, student presentations, and discussions in the class will be based on primary scientific literature.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Life depends on the propagation of genetic material from one generation to next through cycles of genome replication and cell division. We will focus on chromosomes as discrete entities, rather than collections of genes, that are inherited between cell cycles and across generations. By reading selected primary literature covering several decades, we will build an understanding based on key experiments and insights, focusing on chromosomes and their associated molecular machinery. Topics may include kinetochores and microtubule dynamics, centromeres, the mitotic checkpoint, chromosomal instability and cancer, genetic conflict, chromosome evolution, and artificial chromosomes.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for students in graduate level degree programs with an interest in developing a strong understanding of core concepts in cellular and molecular biology and how these concepts translate to therapeutic agents. It is assumed that students either have familiarity with undergraduate level biology topics, or can quickly catch up to keep pace with the course. We will explore areas of cell and molecular biology ranging from protein synthesis to cell signaling to immunology. This fast- paced course will provide both an overview of foundational principles, as well as modern applications and developments through literature review. Students will be expected to engage deeply with the material, and will have the opportunity to develop scientific skills in critical thinking, reading, and communication, culminating in a final group presentation at the end of the semester. Upon completing the course, students should feel empowered to enroll in any advanced molecular and cellular-based biology course at Penn.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will investigate neural processing at the systems level. Principles of how brains encode information will be explored in both sensory (e.g. visual, auditory, social, etc.) and motor systems. Neural encoding strategies will be discussed in relation to the specific behavioral needs of the animal. Examples will be drawn from a variety of different model systems.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

A fundamental goal of neuroscience is to understand how neural circuits in the brain function to influence behavior. The aim of this course is to highlight the neural basis of behavior and discuss modern approaches and novel methods to study the neuronal control of classically studied aspects of behavior. Through a combination of discussions, student presentations, and interactive lectures, we will explore the neural systems that regulate the interactions an animal has with the external world. We will explore sensory systems (such as vision, taste, and olfaction), motor systems, and survival behaviors (such as feeding, drinking, mating, and aggression). The course evaluation will be based largely on written work, participation, and presentations.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Animals display extraordinary diversity in their morphology, physiology, and behavior. Traditionally, these topics have been mostly studied from an ecological perspective. This course will focus on recent advances and discoveries that address the underlying biological mechanisms of animal diversity. Specific topics will include the genetic, molecular, and developmental basis of animal morphological diversity, and genetic, molecular, and neural basis of animal behavioral diversity. Students will gain an understanding of how animal diversity is encoded at the different levels of biological organization. The course will be comprised of lectures to introduce topics, discussion of primary literature, and in-class activities.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Environmental Chemistry (Complete a minimum of 4CUs in Biological, Organic, Inorganic, or Physical Chemistry, plus an additional 2CUs in Environmental Chemistry)

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Advanced seminar on current topics in human genomics and human evolution. Topics include the methods used for phylogenetic and population genetic analysis; detecting variation in the human genome; detecting signatures of natural selection; mapping genetic variation associated with normal variation and with disease risk. This course is designed for advanced undergraduates and graduate students with a strong background in genetics. Spring, even numbered years only Also Offered As: CAMB 5220 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will be a focused study of genomes, genomic techniques, and how these approaches are and will be used in diagnosing and treating human disease. Topics will include genome sequencing, analysis of sequences and microarrays, and new techniques including high- throughput sequencing and reverse genetic analysis with a focus on genome-wide mutant collections.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

conflict, and pathogens shape modern genomes

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course investigates epigenetic phenomena: heritable alternate states of gene activity that do not result from an alteration in nucleotide composition (mutations). Epigenetic mechanisms regulate genome accessibility and cell differentiation. They play a key role in normal development and in oncogenesis. For example both mammalian X- chromosome inactivation and nuclear transfer (cloning) are subject to epigenetic regulation. Amongst the epigenetic mechanisms we will discuss in this course are chromatin organization, histone modification, DNA methylation and non-coding RNAs. The course is geared toward advanced undergraduate and beginning graduate students and is a combination of lectures, student presentations and research presentations by guest speakers. Students will work with the current scientific literature.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

The logic and methodology of genetic analysis in plants and animals. This lecture course will focus on the use of mutations to study gene function and higher order biological processes, methods for reporting and manipulating gene expression, and analysis of the genetic basis of natural variation. Not Offered Every Year 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Prerequisite

BIOL 2210

Development is the process by which organisms grow and acquire their final shape. This remarkably complex process requires exquisite spatiotemporal control, and principles of developmental biology have implications for nearly all other biological disciplines. This course is a deep dive into these general biological principles, using plants as a model system. Students will prepare presentations on primary literature and engage in vigorous discussions in a "journal club" format. Our goal is to learn how developmentally significant genes and cellular interactions control differentiation and pattern formation.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

and Biotechnology: Genomics and Omics

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for advanced undergraduate and graduate students who are interested in molecular physiology of sensory signal transduction. The major topics to cover will be signal transduction mechanisms used by membrane ion channels and receptors that detect the sensory stimuli (light, sound, temperature, smell and taste, for example) and transmit the signals to the nervous system. Modern molecular, genetic and structural techniques (electrophysiology, protein structural determination/analysis, animal genetics, and human disease, for example) will be introduced along with each topic. References will be primary research articles. Students will critically evaluate research discoveries through analysis of research papers. Each student will deliver two presentations and write a 10-page research proposal.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is designed for students who are interested in understanding how physiological functions are achieved. Taking advantage of the recent explosion in genetic data and high-resolution protein structure analysis across organisms, the course focuses on the evolution of physiological functions at the genetic, structural, circuit and organismal levels. Examples include the co-evolution of toxins and toxin resistance between hunter and prey, the evolution of substance transport across cell membranes, intracellular signaling cascades, intercellular communication, distributed and centralized nervous systems, neural circuits controlling physiological functions such as feeding, locomotion and visual information processing. Students are expected to learn 1) basic physiological processes, their origin and adaptation, 2) modern genetic, structural and physiological techniques, 3) to critically evaluate research findings, 4) to present scientific papers, and 5) to write a research report. Spring, odd numbered years only Mutually Exclusive: BIOL 4314 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Prerequisite

NRSC 1110 OR BIOL 2310 OR BIOL 2210 OR BIOL 2110

the muscular system The course will focus on muscle function from the level of molecules to whole animal locomotion. At each level of organization, muscle function will be explored from mechanical and energetic viewpoints. The course will include lectures, demonstrations, and several guest expert lectures. Students will also be introduced to realistic musculo-skeletal modelling and forward dynamic simulations to explore integrated function.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Theories and mechanisms of evolution, with emphasis on the genetic basis of evolutionary change.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will focus on fundamental topics related to the ecological and evolutionary processes driving the transmission of pathogenic microbes among hosts including life-history strategies; evolution of pathogenic traits; the impacts of temporal, spatial and host-trait heterogeneity; and factors causing the emergence of an infectious pathogen. Examples will be drawn from human, wildlife, and plant pathogens to illustrate these ecological and evolutionary topics. Students will learn to develop and apply current ecological and evolutionary theory to infectious microbe research and gain practical experience accessing, interpreting and synthesizing the peer-reviewed scientific literature through a combination of popular and scientific readings, discussion, and lecture.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Introductory probability theory. Principles of statistical methods. Problems of estimation and hypothesis testing in biology and related areas.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course focuses on the underlying principles, implementation, and interpretation of statistical methods commonly used in biology. Lectures will incorporate exercises that implement these analyses in the open source software R, as well as exercises in data visualization. We will draw on examples from ecology, evolution, genetics, and genomics.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Introduction to basic theoretical tools to study the evolutionary and ecological dynamics of populations. Topics to be discussed include: basic population dynamics and population genetics theory, evolutionary game theory/adaptive dynamics, social evolution (kin selection/multilevel selection), life-history evolution, and stochastic models. Other topics may be added based on the specific interests of students in the class.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

The goal of this course is to develop a deeper understanding of techniques and concepts used in Computational Biology. Both theoretical and practical aspects of a range of methods will be covered. Theoretical aspects will include statistical analysis, modeling, and algorithm design. This course cannot provide a comprehensive survey of the field but focuses on a select core set of topics and data types. We will discuss the genome browser, alignment algorithms, classical and non-parametric statistics, pathway analysis, dimensionality reduction, GWAS, multiple testing and machine learning, with primary focus on biomedical data. UNIX, R and Python will be utilized to learn to execute big data analysis pipelines, including RNA-Seq and DNA-Seq. UNIX and R will be taught from first principles but prior experience in Python will be assumed. You will be provided with a computational (cloud based) platform on which to do all programming and assignments. Prerequisite: Programming experience in Python required.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Select one of the following additional science courses:

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This is a course for PhD students in natural sciences with interests in applying latest machine learning and AI approaches to their problem domains. The course will consist of directed readings and covering available tutorials with weekly discussions. The goal is to motivate mutual self-learning through guided discussions. Weekly participation and completion of readings or other assigned materials is essential and lack of attendance will be graded. Topics to be covered will be decided after the first meeting. Prerequisites: multivariate calculus, linear algebra statistics, and probability. Not Offered Every Year Also Offered As: PHYS 5566 1 Course Unit University of Pennsylvania Catalog 1223

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Mathematical modeling is increasingly becoming a standard technique in physiology and cell biology. In this class, we will cover some classical models in physiology and cell biology. Half of the course will be devoted to electrophysiology (Hodgkin-Huxley model, action potential propagation and related topics), which has arguably been the most successful area of application of mathematical techniques to biology. We will then consider models of molecular motors and muscle mechanics, of pattern formation and cell polarization. Not Offered Every Year Also Offered As: AMCS 5681 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Course for graduate students planning research in computational biology and genomics. Assigned readings will cover algorithms and data analysis techniques in computational biology. The course will include presentations and discussion of research problems involving computational analysis. Active group participation is required. Topics could include string algorithms, probability theory, multivariate statistics, molecular evolution, Markov Models, phylogenetic trees, and machine learning. Not Offered Every Year 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course focuses on teaching students the Pennsylvania flora, both native and naturalized. Through weekly field trips, students will gain an appreciation for the diversity of plant species and plant communities in PA, and observe and discuss ecological and historical forces that influence plant species occurrences and plant communities. The ability to quickly and accurately identify plants in the field, through both sight identification and the use of a dichotomous key, is the major thrust of this course. Students will also learn how to appropriately collect plant materials for further study/identification in the laboratory and for archiving in an herbarium collection. Mutually Exclusive: BIOL 4600 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Prerequisite

((BIOL 1101 AND BIOL 1102) OR BIOL 1124)

Urban environments present unique challenges and opportunities for plant species. After a review of plant taxonomy and anatomy, this course will examine the ecological impacts of plants in urban settings. We will explore landscapes in and around Penn’s campus to understand how plant communities contribute to ecosystem services in these environments. The applied uses of plants in agriculture, medicine, bioremediation, and other aspects of community health will also be , explored.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Survey of the physical, chemical and biological properties of freshwater ecosystems, both riverine and lentic, natural and polluted.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course is a lab/lecture/seminar hybrid that will meet once per week for three hours. Each session will consist of mini-lecture/lab, paper discussions/lab, or solely lab efforts. All reading assignments will be available on Canvas (no textbook fees). We will exam various aspects of photosynthesis, water relations and nutrient acquisition in the context of the evolutionary progression of higher plants. With each subject, we will consider, measure, and in some cases model whole-plant physiology while examining sub-cellular-level controls and ecosystem-to-global- level consequences. This course is designed to give molecular biologists through earth-system scientists the tools to measure and understand whole-plant physiological responses to molecular manipulation and environmental variability. All students will learn to appreciate the contex of their work on both micro and macro scales.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Microbiology plays a central role in diverse areas of human life such as infectious disease, ecology, and biotechnology. This course will cover aspects of modern microbiology with an emphasis on prokaryotic organisms. The topics will include basic aspects of microbial diversity, genetics, virology, and pathogenesis as well as examples of applied microbiology.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This laboratory course provides students with a robust microbiological skill set while also giving an opportunity to participate in an authentic research project that may lead to novel antimicrobial discoveries. In the first half of the class students will be given a set of unknown bacteria to identify using biochemical and genetic analysis. Basic and advanced skills in handling bacteria will be learned here. The unknown project will culminate with an in-class presentation. The second half of the course will be an independent research project using soil samples and focused on developing scientific skills. The soil independent project will end in a poster presentation to the class. Microbiological skills will be taught but it will be assumed that you have had an introductory biological lab experience.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course will cover research articles from both the classic and contemporary literature on the genetics, cell biology, and physiology of prokaryotes. The material will focus on a small number of subjects in depth, with an emphasis on how the field has arrived at its current state of knowledge and on exciting new research directions. Possible topics include: stress responses, cell signaling, subcellular organization, bacteriophages, microbial communities, and host-microbe interactions. Spring, even numbered years only Mutually Exclusive: BIOL 4710 1 Course Unit 2026-27 Catalog | Generated 08/03/26

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Prerequisite

BIOL 2210 OR BIOL 3710

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

This course provides a thorough interdisciplinary overview of the modern drug discovery and development process. Building on foundational life sciences and molecular science courses, this course demonstrates how basic scientific concepts are applied to real-world challenges in drug discovery and development. The course begins with a history of medicines in society and the evolution of the modern pharmaceutical and biotech industry. It then covers a wide range of topics, including the identification of novel therapeutic targets, the molecular design of safe and effective drugs, considerations related to the final clinical formulations, clinical trial design and execution, regulatory pathways for drug approval, and post-market safety and efficacy monitoring. The curriculum is led by experienced researchers, biotech innovators, and professionals from both academia and the biopharmaceutical industry. It covers essential disciplines that are vital to drug discovery and development. In addition to core subjects such as physiology, cell biology, molecular biology, and biochemistry, the course also explores related fields, including organic chemistry, medicinal chemistry, pharmacology, pharmacokinetics, toxicology, materials science, and biotechnology. Students will also investigate in silico methodologies, explore applications of AI in drug discovery and development, and learn about advanced biomanufacturing processes. By the course's end, students will understand the various challenges, opportunities, and career paths available within drug discovery, the pharmaceutical sector, and the broader biotechnology industry. Prerequisite: Undergraduate courses in biology, biochemistry, and organic chemistry.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Designed for graduate students with an interest in exploring important discoveries in the biological sciences through the lens of literature discussion. We will emphasize work that has won the Nobel Prize in Physiology or Medicine, and its relevance to modern research. It is assumed that students have familiarity with undergraduate biology topics, or can catch up, to keep pace with discussions. In addition to instructor-guided exploration of course material, students will be expected to lead journal club-style discussions on papers of their choosing. Upon successful completion of this course, students will have both a greater appreciation for major discoveries in the biological sciences, and a greater ability to discuss and apply these discoveries to their own scientific questions.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Intensive laboratory class where open-ended, interesting biological problems are explored using modern lab techniques. Topics may include protein structure/function studies; genetic screens, genomics and gene expression studies; proteomics and protein purification techniques; and molecular cloning and DNA manipulation. The course emphasizes developing scientific communication and independent research skills. Course topics reflect the interests of individual Biology faculty members. This course is recommended for students considering independent research. Mutually Exclusive: BIOL 4825 1 Course Unit

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Prerequisite

BIOL 2810 OR BIOL 2010 OR BIOL 2210

This course will cover various mathematical models and tools that are used to study modern biological problems. Mathematical models may be drawn from cell biology, physiology, population genetics, or ecology. Tools in dynamical systems or stochastic processes will be introduced as necessary. No prior knowledge of biology is needed to take this course, but some familiarity with differential equations and probability will be assumed.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Laboratory research for the Master's of Science in Biology submatriculation program. Apply at the Academic Office, 102 Leidy Labs.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Basic science writing and presentation skills for PhD students in Biology. Designed for second year graduate students preparing for qualifying exams. In the first half of the course, students will produce weekly writing assignments and critique writing submitted by others. In the second half, students will learn techniques for effective research presentations in both seminar style environments and chalk-talk settings.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Integrative seminar on current biological research for first-year PhD students.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Master's ThesisFall or Spring3 Course Units

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Dissertation research for PhD students in Biology.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu

Advanced laboratory reserach with a member of the Biology Graduate Group.

Subject

BIOL

Type

course

Edition

2026-2027

Source

catalog.upenn.edu