BCH

3 Laboratory Practices 3 BCH 220 Role of Biotechnology in Society 3

Subject

BCH

Credits (min)

3

Credits (max)

3

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

or ALS 103 First-year Success in Agriculture and Life Sciences or ALS 303 Transfer Success in Agriculture and Life Sciences or LSC 103 Exploring Opportunities in the Life Sciences English & Advanced Writing

Subject

BCH

Credits (min)

1

Credits (max)

1

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Role of Biotechnology in Society is an introductory science course that takes a semi-technical look at the emerging role of biotechnology in human society. Expectations are that students will gain an appreciation for biotechnology and gain the ability to understand how biotechnology works. Offered only in Poland through Study Abroad Program (4-week course). GEP Interdisciplinary Perspectives Typically offered in Summer only Graduate Catalog 953

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

BIO 181, CH 101

This course provides a descriptive survey of the concepts of physical chemistry with emphasis on their use in applications designed to characterize and manipulate biological molecules and systems. Topics are drawn from thermodynamics (bonding, protein folding energies, linkage, specostropic and differential scanning calorimetric binding measurements), kinetics (enzymatic catalysis, perturbation techniques), statistical mechanics (distributions, ensembles, molecular mechanical & dynamics calculations), electrochemistry, hydrodynamics (diffusion, friction, electrophoresis, viscosity, sedimentation, organism size and shape), quantum mechanics (wave functions operators, uncertainty principle, dipoles, orbitals and resonance energy coupling), and spectroscopy (absorbance and light scattering, fluorescence, nuclear and electronic paramagnetic resonance, MR imaging and x-ray diffraction). P: (CH 201 or CH 203) and (BCH 351 or BCH 451) and (MA 231 or MA 241) and (PY 208 or PY 212) Typically offered in Spring only Biochemistry (BCH) 1

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

This course is an introduction to the basic principles of biochemistry. It emphasizes biochemical structures, properties, and functions, including enzyme kinetics and major metabolic processes. It can serve as a prerequisite for BCH 452 with permission of the department. This course is designed for those students who are not majoring in Biochemistry and do not require a more comprehensive introduction to biochemistry. It is not intended for graduate students. Credit is not allowed for both BCH 351 and BCH 451. Prerequisites required are BIO 183 and one of the two following pathways in chemistry: CH 101/102 (CH 103/104), CH 221/222 (CH 225/226), CH 223/224 (CH 227/228); or CH 101/102 (CH 103/104), CH 201/202 (CH 203/204) , CH 221/222 (CH 225/226). CH 201/202 and CH 223/224 are strongly recommended, if planning to pursue further biochemistry. and CH 101 and CH 201 and CH 221 or by department permission. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

Bio 183 and CH 101 and CH 221 and CH 223; Or Bio 183

Introduction to and survey of the fundamental principles of biochemistry, emphasizing the chemistry of living organisms, chemical structures, and interactions of and between biomolecules. CH 203), CH 202 (or CH 204), CH 221 (or CH 225), CH 222 (or CH 226), CH 223 (or CH 227), CH 224 (or CH 228), and BIO 183 Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

4

Credits (max)

4

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

CH 101 (or CH 103), CH 102 (or CH 104), CH 201 (or

Laboratory experiences in this course are designed to compliment the first semester undergraduate biochemistry course, BCH 451. Basic skills to be mastered include the use of volumetric equipment, spectrophotometers, chromatography, and electrophoresis. You will also learn to assay small quantities of biological materials and analyze lab data. You will learn to manipulate biochemical materials from three of the four major subgroups: proteins, nucleic acids and carbohydrates. You will determine structural elements at a number of analytical levels and learn how to think about their functional capabilities. We will emphasize theoretical information, while discussing how the techniques work. The explanations discuss how the techniques work. We focus on how consecutive methods are interconnected to form process chains. P: CH 101 (or CH 103), CH 102 (or CH 104), CH 201 (or CH 203), CH 202 (or CH 204), CH 221 Organic Chemistry I (or CH 225), CH 222 (or CH 226), CH 223 (or CH 227), CH 224 (or CH 228), BIO 183 and

Subject

BCH

Credits (min)

2

Credits (max)

2

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Select one of the following: 3-4 1,6

Subject

BCH

Credits (min)

3

Credits (max)

3

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Hands on experience with the techniques of molecular biology and protein purification. Cloning and expression of a eukaryotic gene in bacteria will be performed followed by purification of the eukaryotic gene product. Microanalysis of DNA, RNA and protein. Typically offered in Fall and Spring BCH 455/BCH 555 Proteins and Molecular Mechanisms (3 credit hours) Principles of protein structure and function, protein folding, enzymology, ligand binding, protein transport, and metabolic pathways. Typically offered in Fall and Spring

Subject

BCH

Credits (min)

4

Credits (max)

4

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

BCH 451 & BCH 452; Corequisite: BCH 453 BCH 451, BCH 453/553

Subject

BCH

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

A learning experience in agriculture and life sciences within an academic framework that utilizes facilities and resources which are external to the campus. Contact and arrangements with prospective employers must be initiated by student and approved by a faculty adviser, the prospective employer, the departmental teaching coordinator and academic dean prior to the experience. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

1

Credits (max)

6

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

Sophomore standing

Subject

BCH

Credits (min)

1

Credits (max)

1

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Offered as needed to present materials not normally available in regular BCH departmental courses or for new BCH courses on a trial basis. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

1

Credits (max)

5

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

Junior standing.

An advanced laboratory to give students practical experiences in purification and quantitative characterization of enzymes and nucleic acids. Studies with carbohydrates and membrane lipids. Credit may be applied toward biotechnology minor. Typically offered in Fall and Spring BCH 553/BCH 453 Biochemistry of Gene Expression (3 credit hours) Structure and function of nucleic acids and proteins. Synthesis of DNA, RNA, and proteins. Gene expression and Regulation. Methodologies of recombinant DNA research. Credit is not allowed for both BCH 453 and BCH 553. Typically offered in Fall, Spring, and Summer BCH 555/BCH 455 Proteins and Molecular Mechanisms (3 credit hours) Principles of protein structure and function, protein folding, enzymology, ligand binding, protein transport, and metabolic pathways. Typically offered in Fall and Spring

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

BCH 452;BCH 453 BCH 451, Corequisite: GN 311, MB 351 BCH 451, BCH 453/553

FS (MB) 725 Fermentation Microbiology ST (GN) 721 Genetic Data Analysis

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

BCH(ANS) 571 Regulation of Metabolism

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Introduction to molecular biology for teachers. Emphasis will be on developing basic laboratory skills applicable to middle or high school biology classes. Teachers will develop their own labs during the last week of class. This is an intensive three-week class, five hours per day. Students should have at least one biotechnology course before enrolling in this course. Prior secondary school teaching experience preferred. Typically offered in Summer only This course is offered alternate even years BCH 571/ANS 571 Regulation of Metabolism (3 credit hours) Study of hormonal, enzymatic and molecular-genetic regulation of carbohydrate and lipid metabolism; emphasis on mammalian species. Typically offered in Fall only This course is offered alternate odd years

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Subject

BCH

Credits (min)

3

Credits (max)

3

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

The study of topics of special interest by small groups of students instructed by members of the faculty. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

1

Credits (max)

6

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

BCH 451

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

The study of topics of special interest by small groups of students instructed by members of the faculty. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

1

Credits (max)

6

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

BCH 451

BCH(TOX) 660 Free Radicals in Toxicology

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Performance of highly directed research by biochemistry students in one or more laboratories of student's choice prior to beginning thesis research. Each laboratory experience lasts 5 weeks and given 1 hr. of credit. No more than 4 credits earned inBCH 692. Typically offered in Fall and Spring

Subject

BCH

Credits (min)

1

Credits (max)

1

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

BCH 451

Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment. Typically offered in Fall and Spring

Subject

BCH

Credits (min)

1

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Master's student

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

For students in non-thesis master's programs who have completed all other requirement of the degree except preparing for and taking the final master's exam. Typically offered in Spring only

Subject

BCH

Credits (min)

1

Credits (max)

9

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Master's student

Instruction in research and research under the mentorship of a member of the Graduate Faculty. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

1

Credits (max)

9

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Master's student

Total Hours 30 Every semester for 2 years, 4 credit hours total; 1/semester Students may choose other courses approved in conjunction with the academic committee Credit hours flexible to meet 30 total hours

Subject

BCH

Credits (min)

1

Credits (max)

1

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research. Typically offered in Summer only

Subject

BCH

Credits (min)

1

Credits (max)

1

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Master's student

For students who have completed all credit hour requirements and full- time enrollment for the master's degree and are writing and defending their thesis. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

1

Credits (max)

9

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Master's student

Introduction to the current understanding and methods used for the study of structures, thermodynamics and conformational dynamics of proteins, nucleic acids and membranes. recommended Typically offered in Fall only in

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

BCH 453 or BCH 553; a course in physical chemistry highly

hours) Biochemistry of DNA replication, transcription, RNA processing and translation. Development of key concepts, techniques and applications relating to mechanisms and regulation of these processes by analysis of primary literature. Typically offered in Spring only

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

BCH 453 or BCH 553

Regulation of cellular processes, membrane structure and function, signal transduction, protein trafficking/sorting, secretion, photosynthesis and nitrogen fixation. Typically offered in Fall only

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

BCH 701 or BCH 703

On demand. Theory and application of scanning electron microscopy, including specimen preparation, microscope alignment and operation, performance evaluation, interpretation of problems and darkroom technique. (Limited to 8 students with prior approval of instructor.) Typically offered in Spring only

Subject

BCH

Credits (min)

2

Credits (max)

2

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

Graduate standing with some biological background

BCH(GN) 761 Advanced Molecular Biology of the Cell

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

credit hours) Basic principles and practice of protein crystallography and the application of molecular dynamics to evaluate structural models. The computer lab provides hands-on experience in structure determination, refinement, model building, and molecular dynamics using CHARMM. Typically offered in Fall only This course is offered alternate odd years BCH 761/GN 761/PB 761 Advanced Molecular Biology Of the Cell (3 credit hours) An advanced graduate class involving integrated approaches to complex biological questions at the molecular level, encompassing biochemistry, cell biology and molecular genetics. The course will focus on an important, current area of research in eukaryotic biology using the primary scientific literature, and will involve class discussions, oral presentations, and a written research proposal. Typically offered in Spring only This course is offered alternate years

Subject

BCH

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

BCH 455 or BCH 555 or equivalent

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

BCH(GN) 768 Nucleic Acids: Structure and Function

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Subject

BCH

Credits (min)

3

Credits (max)

3

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

An advanced course in enzyme kinetics and mechanisms with particular emphasis on experimental design and interpretation. The first half of the course covers the derivation and application of single and multisubstrate kinetic equations, inhibition and pre-steady state kinetics. The second half of the course covers fundamental chemical and physical principles of enzyme catalysis and specificity. Typically offered in Spring only This course is offered alternate even years

Subject

BCH

Credits (min)

3

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

catalog.ncsu.edu

Prerequisite

BCH 451 and BCH 455/555 or equivalent.

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

The study of topics of special interest by small groups of students instructed by members of the faculty. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

1

Credits (max)

6

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

BCH 451

BCH(TOX) 860 Free Radicals in Toxicology

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Performance of highly directed research by biochemistry students in one or more laboratories of student's choice prior to beginning thesis research. Each laboratory experience lasts 5 weeks and given 1 hr. of credit. No more than 4 credits earned inBCH 692. Typically offered in Fall only

Subject

BCH

Credits (min)

1

Credits (max)

1

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

BCH 451

Teaching experience under the mentorship of faculty who assist the student in planning for the teaching assignment, observe and provide feedback to the student during the teaching assignment, and evaluate the student upon completion of the assignment. Typically offered in Fall and Spring

Subject

BCH

Credits (min)

1

Credits (max)

3

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Doctoral student

For students who are preparing for and taking written and/or oral preliminary exams. Typically offered in Spring only

Subject

BCH

Credits (min)

1

Credits (max)

9

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Doctoral student

Instruction in research and research under the mentorship of a member of the Graduate Faculty. Typically offered in Fall, Spring, and Summer

Subject

BCH

Credits (min)

1

Credits (max)

9

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Doctoral student

Subject

BCH

Credits (min)

1

Credits (max)

9

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

For graduate students whose programs of work specify no formal course work during a summer session and who will be devoting full time to thesis research. Typically offered in Summer only

Subject

BCH

Credits (min)

1

Credits (max)

1

Credit unit

credit hours

Type

course

Edition

2026-2027

Source

grad.ncsu.edu

Prerequisite

Doctoral student

area. - Half-Time Registration - Full-Time Registration

Subject

BCH

Type

course

Edition

2026-2027

Source

grad.ncsu.edu