North Carolina State University at Raleigh · Courses
BEC
32 courses with the subject BEC, each shown exactly as we captured it from the college's catalog, with every element we hold. Where the wording looks broken, that is our reading of the catalog, not the college's text.
BEC 220Introduction to Drug Development and Careers in
Biomanufacturing (1 credit hours) Introduction to discovery and development of biopharmaceuticals, industrial enzymes, food ingredients and biologics. Discussion of majors that prepare students for positions in the biotechnology industry. Lectures from staff and from professionalsin the biotechnology industry focus on drug development, biopharmaceutical process development, design of biomanufacturing facilities, overview of methods used for manufacturing biopharmaceuticals, drug and enzyme purification, formulation, as well as careers in FDA compliance documentation related to manufacturing products using microbial biotechnology. Typically offered in Fall and Spring
Offered as needed to present materials not normally available in regular course offerings or for offering of new courses on a trial basis. Departmental approval required. Typically offered in Fall, Spring, and Summer
Introduction to biomanufacturing research through experimental, theoretical, and literature studies. Oral and written presentation of reports. Departmental approval required. Individualized/Independent Study and Research courses require a Course Agreement for Students Enrolled in Non-Standard Courses be completed by the student and faculty member prior to registration by the department. Typically offered in Fall, Spring, and Summer Graduate Catalog 973
Techniques (2 credit hours) This 8 week graduate course introduces engineering students to bioanalytical testing to processes that produce structurally complex biopharmaceuticals. Students will gain hands-on experience including assay validation, drug/biologic substance characterization (structural and activity) and biopharmaceutical purity. The technologies and related theory will include rapid micro SDS-PAGE, lab-on-a-chip, HPLC, mass spectrometry, UV/Vis absorbance and fluorescence spectroscopy. Students will also learn assay development and validation concepts as per ICH Q2(R1) and other U.S. and international government regulatory guidelines. Typically offered in Fall only BEC 525/BEC 425 Molecular Biology for Biomanufacturing (2 credit hours) This course is an introduction to fundamental molecular biology techniques, applied to generate bacterial cell lines for the production of recombinant proteins. Course material provides a comprehensive description of an expression system, with emphasis on the central dogma of molecular biology, detailed gene structure, vector components and bacterial host cell characteristics. Different genetic, physiologic and growth condition aspects are included to ensure the overproduction of a functional protein of interest. This comprises different molecular approaches for gene cloning, bacterial selection/screening and regulation of genetic expression. The course provides hands-on experience during laboratory sessions, where students isolate a gene of interest, clone the gene into an expression vector, transform bacteria, select for positive clones, grow recombinant cells, and induce the production of the protein of interest. Techniques such as SDS-PAGE, Western blot, and ELISA are used for the detection and quantification of the active recombinant protein. Typically offered in Fall and Spring BEC 526/BBS 426/FS 426/BEC 426/BBS 526/FS 526 Upstream Biomanufacturing Laboratory (2 credit hours) This course is an introduction to current food manufacturing practice (CGMP) as applied to the growth of microbial cells in bioreactors. Hands-on experience is obtained in the operation and control of 30 liter bioreactors to study agitation, oxygen transfer, cleaning, sterilization, media preparation and the growth of recombinant E. coli for protein production. Credit will not be awarded in both BBS 426 and BBS/FS 526. This is an eight week course. Typically offered in Fall and Spring
Weekly seminars on topics of current interest in biomanufacturing and affiliated subjects. Seminars will be presented by resident faculty members, graduate students and visiting lectures from industry, government regulatory agencies such as the FDA or from academic programs related to biomanufacturing. Typically offered in Fall and Spring
Offered to present graduate course content not available in existing courses or for offering of new graduate courses on a trial basis for S/U courses. Departmental approval required. Typically offered in Fall, Spring, and Summer
Introduction to biomanufacturing research through experimental, theoretical and literature studies under the mentorship of a member of the graduate faculty. Oral and written presentation of reports. Deptartmental approval required. physical science Typically offered in Fall, Spring, and Summer
